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Gonadal development and function after immature testicular tissue banking as part of high-risk gonadotoxic treatment
Are we offering immature testicular tissue banking to the right patients? The clinical follow-up data of 59 boys treated with high-risk gonadotoxic treatment demonstrate no additional risk related to the testicular biopsy procedure itself, but a substantial risk for impaired gonadal development after high-risk gonadotoxic treatment (in particular myeloablative conditioning prior to HSCT).